Real-world performance methodology
Evaluation methods for concordance, change attribution and failure analysis against documented laboratory comparators.
Intelligence for Genomics
We build the products genomic science needs to scale.
From a VCF to a clinical report
Folklore brings classification, evidence, phenotype and prioritisation into one case view. A qualified professional reviews the final interpretation.
- Panels, exomes and whole genomes
- Classification, evidence and prioritisation
- Model-assisted interpretation under clinical review
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We build computational methods, genomic infrastructure and clinical systems
Helena brings together genomic methodology, high-performance computing and clinical software engineering. Each layer is developed as part of the same system, from the treatment of evidence and reference data to the way results reach laboratory review.
We develop the methods behind genomic interpretation
We develop methods for classifying genetic variants and evaluating their performance against laboratory results. We publish our work in papers, preprints and technical documentation.
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Latest news
How we started building Folklore in Bulgaria
Folklore at Crossroads 2026 in Sofia
Helena presents Folklore at the Enterprise Europe Network meeting in Sofia
Making genomic interpretation more accessible: our Bloomberg TV Bulgaria interview
Our paper on variant classification studies is published in Frontiers in Genetics
Helena Bioinformatics and ELTA 90 Announce Exclusive Distribution Partnership in Bulgaria
Work with us
We at Helena Bioinformatics work with laboratories, universities and research organisations on genomic interpretation, validation and clinical implementation.
